NeoGenix XP
Safe and clinically proven natural bone substitute
NeoGenix XPTM is an osteoconductive, porous, anorganic bone mineral with carbonate apatite structure derived from porcine cancellous bone and has the following features:
- Carbonate apatite structure similar to natural bone mineral
- Highly porous - more space available for new bone deposition
- Rough surface - facilitates cell adhesion and spread for bone ingrowth
- Osteoconductive
- Available in a jar or delivery syringe
Safe
- Porcine animals are considered a non-TSE relevant species
- Bone tissue is subjected to several processing steps known to eliminate or inactivate viruses
- A rigorous process designed to effectively mitigate any risk of disease transmission and ensure safety for human implantation
- The bone graft is provided sterile and for single use only
Carbonate apatite anorganic bone mineral
- Carbonate apatite structures are better osteoconductive materials than hydroxyapatite 1,2,3
- Resorption and remodeling profiles are more similar to natural bone than those of synthetic materials, such as hydroxyapatite or tricalcium phosphate 2
Porous
- Porosity permits vascularization of the defect site and enhances osteogenesis 4,5
- High porosity and large pores enhance bone ingrowth and osseointegration of the implant after surgery 5
- NeoGenix XPTM macropores range between 0.1 mm – 1.0 mm 6
Contact your local representative for product availability details. All products are not available on every market.
References 1.Spense G., Patel N., Brooks R., Rushton N. 2010. Osteoclastogenesis on hydroxyapatite ceramics: The effect of carbonate substitution. J Biomed Mater Res A. 2010 Mar 15;92(4):1292-300. 2.Ellies LG, Carter JM, Natiella JR, Featherstone JDB, Nelson DGA. 1988. Quantitative Analysis of Early In Vivo Tissue Response to Synthetic Apatite Implants. J Biomed Mater Res 22:137–148. 3.Landi E., Celotti G., Logroscino G., Tampieri A. 2003. Carbonated Hydroxyapatite as Bone Substitute. Journal of the European Ceramic Society 23: 2931–2937. 4.Frank M. Klenke, Yuelian Liu, Huipin Yuan, Ernst B. Hunziker, Klaus A. Siebenrock, Willy Hofstetter. Impact of Pore Size on the Vascularization and Osseointegration of Ceramic Bone Substitutes in vivo. Journal of Biomedical Materials Research Part A, 2007, 777-786 5.Hannink G1, Arts JJ. Bioresorbability, porosity and mechanical strength of bone substitutes: what is optimal for bone regeneration? Injury. 2011 Sep;42 Suppl 2:S22-5. 6.Data on file
Intended Use
NeoGenix XPTM can be used in the following types of dental surgeries:
- Ridge and sinus extraction
- Extraction socket grafting
- Infrabony periodontal defects
- Periodontal defects
- Peri-implant defects
- Dehiscence defects
Surface roughness
Surface roughness affects cellular response, enhancing cell adhesion and proliferation and possibly other markers of expression of cell phenotype, like production of collagen type I, osteocalcin, extracellular matrix and mineralized material.
Assortment
NeoGenix XPTM is available in a jar or delivery syringe.
Material
NeoGenix XPTM is derived from porcine cancellous bone.
Packaging
The bone graft NeoGenix XPTM is provided sterile and for single use only.
Contact your local representative for product availability details. All products are not available on every market.
Manufacturer: Collagen Matrix, Inc., 15 Thornton Road, Oakland, NJ 07436 USA. Authorized EU Representative: MDSS GmbH, Schiffgraben 41, 30175 Hannover, Germany. Distributed by: neoss.com